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United States of America Patent and Trademark Office. Granted Patents (USPTO) >
4152432
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Patent Details
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Inventor
Heymes Rene Lutz Andre
Assignee
Roussel Uclaf
Attorney
Hammond & Littell
IPC Codes
C07D 277/20 C07D 277/00 A61K 31/545 C07D 501/34
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Patent Office: United States of America Patent and Trademark Office. Granted Patents (USPTO)
Title: 3-Acetoxymethyl-7-
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Application No: 05/817,114
Publication No: 4152432
Application Date: 1977-07-19
Publication Date: 1979-05-01
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Abstract
Compounds of the formula ##STR1## wherein R is selected from the group consisting of hydrogen and groups easily removable by acid hydrolysis or hydrogenolysis, R' is selected from the group consisting of hydrogen, alkyl of 1 to 4 carbon atoms, alkenyl and alkynyl of 2 to 4 carbon atoms and groups easily removable by acid hydrolysis or hydrogenolysis, A is selected from the group consisting of hydrogen, alkali metal and equivalents of an alkaline earth metal or magnesium and an organic amine base with the proviso that when R' is a group easily removable by acid hydrolysis or hydrogenolysis, R is also and when R' is hydrogen, R also is hydrogen and the wavy line means the OR' group may be in either one of the two possible syn or anti positions having antibiotic activity and process for their preparation.
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US4152432 at USPTO
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Referenced by : 71 patent(s) worldwide
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Inventor: Keith Dennis D; Roberts John L; Wei Chung-Chen Assignee: Hoffmann-La Roche Inc Attorney: nullGould George M; Johnston George W; Kass Alan P Title: Cephalosporin antibacterial compounds Patent Office: United States of America Patent and Trademark Office. Granted Patents (USPTO) Document Number: US5162523
Referenced by: 8
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Inventor: Albrecht Harry A; Chan Ka-Kong; Keith Dennis D; Then Rudolf L; Weigele Manfred Assignee: Hoffmann La-Roche, Inc Attorney: nullGould George M; Johnston George W; Kass Alan P Title: Anti-bacterial cephalosporin compounds Patent Office: United States of America Patent and Trademark Office. Granted Patents (USPTO) Document Number: US5147871
Referenced by: 7
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Inventor: Keith Dennis D; Roberts John L; Wei Chung-Chen Assignee: Hoffmann-La Roche Inc Attorney: nullGould George M; Johnston George W; Kass Alan P Title: Penam antibacterial compounds Patent Office: United States of America Patent and Trademark Office. Granted Patents (USPTO) Document Number: US5159077
Referenced by: 4
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Inventor: Nakagawa Susumu; Otake Norikazu; Ushizima Ryosuke Assignee: Banyu Pharmaceutical Co, Ltd Attorney: nullOblon, Fisher, Spivak, McClelland & Maier Title: Cephalosporin derivatives, and antibacterial agents Patent Office: United States of America Patent and Trademark Office. Granted Patents (USPTO) Document Number: US4814328
Referenced by: 4
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Inventor: Keith Dennis D; Wei Chung-Chen; West Kevin F Assignee: Hoffmann-La Roches Inc Attorney: nullGould George M; Johnston George W; Kass Alan P Title: Process for synthesizing antibacterial cephalosporin compounds Patent Office: United States of America Patent and Trademark Office. Granted Patents (USPTO) Document Number: US5112967
Referenced by: 2
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Inventor: Takaya Takao; Inamoto Yoshiko Assignee: Fujisawa Pharmaceutical Co, Ltd Attorney: nullOblon, Spivak, McClelland, Maier & Neustadt Title: 3,7-Disubstituted-3-cephem compounds Patent Office: United States of America Patent and Trademark Office. Granted Patents (USPTO) Document Number: US4868174
Referenced by: 2
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Inventor: Curran William V Assignee: American Cyanamid Company Attorney: nullSzatkowski T S Title: Process for the preparation of intermediates used to produce aminothiazoloximino cephalosporins Patent Office: United States of America Patent and Trademark Office. Granted Patents (USPTO) Document Number: US4959495
Referenced by: 1
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Inventor: Takaya Takao; Masugi Takashi; Takasugi Hisashi; Kochi Hiromu Assignee: Fujisawa Pharmaceutical Co, Ltd Attorney: nullOblon, Fisher, Spivak, McClelland & Maier Title: Syn-isomer of 3,7-disubstituted-3-cephem-4-carboxylic acid compounds and processes for the preparation thereof Patent Office: United States of America Patent and Trademark Office. Granted Patents (USPTO) Document Number: US4804752
Referenced by: 1
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Inventor: Kamiya Takashi; Tanaka Kunihiko; Teraji Tsutomu; Nakai Yoshiharu Assignee: Fujisawa Pharmaceutical Co Attorney: nullStemple Dayton R Title: Amino thiazole compounds Patent Office: United States of America Patent and Trademark Office. Granted Patents (USPTO) Document Number: US4599426
Referenced by: 1
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Inventor: Kurono Masayasu; Baba Yutaka; Mitani Takahiko; Onishi Masao; Kondo Yasuaki; Sawai Kiichi Assignee: Sanwa Kagaku Kenkyusho Co, Ltd Attorney: nullArmstrong, Nikaido, Marmelstein, Kubovick & Murray Title: Trialkylsilyl pyridinium cephalosporin antibiotics Patent Office: United States of America Patent and Trademark Office. Granted Patents (USPTO) Document Number: US4857521
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Reference cited : 5 patent(s) worldwide
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