Advanced Search
     SurfIP >  Directory >  United States of America Patent and Trademark Office. Granted Patents (USPTO) >  4152432 Patent Details    
     
 
          
 
Inventor
Heymes Rene
Lutz Andre


Assignee
Roussel Uclaf


Attorney
Hammond & Littell


IPC Codes
C07D 277/20
C07D 277/00
A61K 31/545
C07D 501/34


Patent Office: United States of America Patent and Trademark Office. Granted Patents (USPTO)   

Title: 3-Acetoxymethyl-7-


Application No: 05/817,114

Publication No: 4152432

Application Date: 1977-07-19

Publication Date: 1979-05-01

 

Abstract
Compounds of the formula ##STR1## wherein R is selected from the group consisting of hydrogen and groups easily removable by acid hydrolysis or hydrogenolysis, R' is selected from the group consisting of hydrogen, alkyl of 1 to 4 carbon atoms, alkenyl and alkynyl of 2 to 4 carbon atoms and groups easily removable by acid hydrolysis or hydrogenolysis, A is selected from the group consisting of hydrogen, alkali metal and equivalents of an alkaline earth metal or magnesium and an organic amine base with the proviso that when R' is a group easily removable by acid hydrolysis or hydrogenolysis, R is also and when R' is hydrogen, R also is hydrogen and the wavy line means the OR' group may be in either one of the two possible syn or anti positions having antibiotic activity and process for their preparation.


US4152432 at USPTO





 
  Referenced by : 71  patent(s) worldwide
 
Inventor: Keith Dennis DRoberts John LWei Chung-Chen
Assignee: Hoffmann-La Roche Inc
Attorney: nullGould George MJohnston George WKass Alan P
Title: Cephalosporin antibacterial compounds
Patent Office: United States of America Patent and Trademark Office. Granted Patents (USPTO)   Document Number: US5162523
Referenced by: 8   
      
 
Inventor: Albrecht Harry AChan Ka-KongKeith Dennis DThen Rudolf LWeigele Manfred
Assignee: Hoffmann La-Roche, Inc
Attorney: nullGould George MJohnston George WKass Alan P
Title: Anti-bacterial cephalosporin compounds
Patent Office: United States of America Patent and Trademark Office. Granted Patents (USPTO)   Document Number: US5147871
Referenced by: 7   
      
 
Inventor: Keith Dennis DRoberts John LWei Chung-Chen
Assignee: Hoffmann-La Roche Inc
Attorney: nullGould George MJohnston George WKass Alan P
Title: Penam antibacterial compounds
Patent Office: United States of America Patent and Trademark Office. Granted Patents (USPTO)   Document Number: US5159077
Referenced by: 4   
    
 
Inventor: Nakagawa SusumuOtake NorikazuUshizima Ryosuke
Assignee: Banyu Pharmaceutical Co, Ltd
Attorney: nullOblon, Fisher, Spivak, McClelland & Maier
Title: Cephalosporin derivatives, and antibacterial agents
Patent Office: United States of America Patent and Trademark Office. Granted Patents (USPTO)   Document Number: US4814328
Referenced by: 4   
    
 
Inventor: Keith Dennis DWei Chung-ChenWest Kevin F
Assignee: Hoffmann-La Roches Inc
Attorney: nullGould George MJohnston George WKass Alan P
Title: Process for synthesizing antibacterial cephalosporin compounds
Patent Office: United States of America Patent and Trademark Office. Granted Patents (USPTO)   Document Number: US5112967
Referenced by: 2   
    
 
Inventor: Takaya TakaoInamoto Yoshiko
Assignee: Fujisawa Pharmaceutical Co, Ltd
Attorney: nullOblon, Spivak, McClelland, Maier & Neustadt
Title: 3,7-Disubstituted-3-cephem compounds
Patent Office: United States of America Patent and Trademark Office. Granted Patents (USPTO)   Document Number: US4868174
Referenced by: 2   
    
 
Inventor: Curran William V
Assignee: American Cyanamid Company
Attorney: nullSzatkowski T S
Title: Process for the preparation of intermediates used to produce aminothiazoloximino cephalosporins
Patent Office: United States of America Patent and Trademark Office. Granted Patents (USPTO)   Document Number: US4959495
Referenced by: 1   
    
 
Inventor: Takaya TakaoMasugi TakashiTakasugi HisashiKochi Hiromu
Assignee: Fujisawa Pharmaceutical Co, Ltd
Attorney: nullOblon, Fisher, Spivak, McClelland & Maier
Title: Syn-isomer of 3,7-disubstituted-3-cephem-4-carboxylic acid compounds and processes for the preparation thereof
Patent Office: United States of America Patent and Trademark Office. Granted Patents (USPTO)   Document Number: US4804752
Referenced by: 1   
    
 
Inventor: Kamiya TakashiTanaka KunihikoTeraji TsutomuNakai Yoshiharu
Assignee: Fujisawa Pharmaceutical Co
Attorney: nullStemple Dayton R
Title: Amino thiazole compounds
Patent Office: United States of America Patent and Trademark Office. Granted Patents (USPTO)   Document Number: US4599426
Referenced by: 1   
    
 
Inventor: Kurono MasayasuBaba YutakaMitani TakahikoOnishi MasaoKondo YasuakiSawai Kiichi
Assignee: Sanwa Kagaku Kenkyusho Co, Ltd
Attorney: nullArmstrong, Nikaido, Marmelstein, Kubovick & Murray
Title: Trialkylsilyl pyridinium cephalosporin antibiotics
Patent Office: United States of America Patent and Trademark Office. Granted Patents (USPTO)   Document Number: US4857521
    

Back to Top

 
  Reference cited : 5  patent(s) worldwide
 
Inventor: Ochiai MichihikoOkada TaiitiAki OsamiMorimoto AkiraKawakita KenjiMatsushita Yoshihiro
Assignee: Takeda Chemical Industries, Ltd
Attorney: nullWenderoth, Lind & Ponack
Title: Thiazolylacetamido cephalosporin type compounds
Patent Office: United States of America Patent and Trademark Office. Granted Patents (USPTO)   Document Number: US4098888
Referenced by: 150    Reference cited: 11   
    
 
Inventor: Ochiai MichihikoMorimoto AkiraMatsushita YoshihiroOkada Taiiti
Assignee: Takeda Chemical Industries, Ltd
Attorney: nullWenderoth, Lind & Ponack
Title: Aminothiazole derivatives
Patent Office: United States of America Patent and Trademark Office. Granted Patents (USPTO)   Document Number: US4008246
Referenced by: 30    Reference cited: 2   
    
 
Inventor: Cook Martin ChristopherGregory Gordon IanBradshaw Janice
Assignee: Glaxo Laboratories Limited
Attorney: nullBacon & Thomas
Title: 3-Hydroxymethyl-7.beta.-(2-alkoxy-or benzyloxyimino-2-arylacetamido)ceph-3-em-4-carboxylic acids and salts thereof
Patent Office: United States of America Patent and Trademark Office. Granted Patents (USPTO)   Document Number: US4033950
Referenced by: 22    Reference cited: 2   
    
 
Inventor: Laundon Brian
Assignee: Glaxo Laboratories Limited
Attorney: nullBacon & Thomas
Title: Cephalosporin compounds
Patent Office: United States of America Patent and Trademark Office. Granted Patents (USPTO)   Document Number: US4007174
Referenced by: 7    Reference cited: 3   
    
 
Patent Office: German Patent and Trade Mark Office (DPMA)   Document Number: DE2556736

Back to Top